The treatment, given to four people with damaged corneas, seems safe but needs to be tested in larger trials.
By Smriti Mallapaty
Twitter Facebook Email
Close up view of a human eye during a slit lamp eye examination.
The transparent cornea is the outermost layer of the eye. Credit: Patrick Landmann/SPL
Three people with severely impaired vision who received stem-cell transplants have experienced substantial improvements in their sight that have persisted for more than a year. A fourth person with severely impaired vision also experienced gains in their sight, but they did not last. The four are the first to receive transplants made from reprogrammed stem cells to treat damaged corneas, the transparent outer surface of the eye1.
Access options
Access through your institution
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
27,99 € / 30 days
cancel any time
Learn more
Subscribe to this journal
Receive 51 print issues and online access
185,98 € per year
only 3,65 € per issue
Learn more
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Learn more
Prices may be subject to local taxes which are calculated during checkout
Additional access options:
Log in
Learn about institutional subscriptions
Read our FAQs
Contact customer support
Nature 635, 533-534 (2024)
doi: https://doi.org/10.1038/d41586-024-03656-z
References
Soma, T. et al. Lancet https://doi.org/10.1016/S0140-6736(24)01764-1 (2024).
Article
Google Scholar
Download references
Reprints and permissions
Latest on:
Stem cells
Regeneration
Cell biology
Ethics must keep pace with embryo research
Correspondence 28 OCT 25
Ancient viral DNA in the human genome shapes early development
News & Views 01 OCT 25
Dietary cysteine enhances intestinal stemness via CD8+ T cell-derived IL-22
Article 01 OCT 25
Nature Careers
Jobs
Tenure Track Assistant Professor – Molecular Medicine
Dallas, Texas (US)
The University of Texas Southwestern Medical Center (UT Southwestern Medical Center)
(Junior/Senior) PI Positions at the Institute for Regenerative Biology and Medicine, CIMR
As part of CIMR, the Institute of Regenerative Biology and Medicine (IRBM) is now looking for outstanding scientists
Beijing (CN)
The Chinese Institutes for Medical Research (CIMR), Beijing
Accelerating Natural Climate Solutions Grants from Allen Family Philanthropies
Environmental scientists: Allen Family Philanthropies is awarding $10M in grants for natural climate solutions projects in the United States.
United States
Allen Family Philanthropies
Senior Scientist, Target Discovery, ADC
We are looking for a motivated and skilled Senior Scientist to join Antibody-Drug Conjugates (ADC) Target Discovery Team.
Turku (Kaupunki), Varsinais-Suomi (FI)
Orion Corporation
Research Scientist, Target Discovery, Immuno-Oncology
We are looking for a Research Scientist within Orion Pharma’s Immuno-Oncology target discovery team.
Turku (Kaupunki), Varsinais-Suomi (FI)
Orion Corporation
Access through your institution
Buy or subscribe
Related Articles
Stem cells reverse woman’s diabetes — a world first
The promise and potential of stem cells in Parkinson’s disease
‘Reprogrammed’ stem cells to treat spinal-cord injuries for the first time
‘Reprogrammed’ stem cells implanted into patient with Parkinson’s disease
Woman is first to receive cornea made from ‘reprogrammed’ stem cells
‘Reprogrammed’ stem cells approved to mend human hearts for the first time
Subjects
Stem cells Regeneration Cell biology
Sign up to Nature Briefing
An essential round-up of science news, opinion and analysis, delivered to your inbox every weekday.
Email address
e.g. jo.smith@university.ac.uk
Yes! Sign me up to receive the daily Nature Briefing email. I agree my information will be processed in accordance with the Nature and Springer Nature Limited Privacy Policy.
Nature (Nature) ISSN 1476-4687 (online) ISSN 0028-0836 (print)