Exosome-based therapies for inflammatorydisorders: a review of recent advances
Page 2 of 19Saleem et al. Stem Cell Research & Therapy (2024) 15:477they have considerable latent drug delivery systems forthe treatment of chronic inflammatory disorders [6]. Fur-thermore, exosomes generated from mesenchymal stemcells (MSCs), astrocytes, and dendritic cells (DCs) frominflammatory sites with immunomodulatory capabilitiesare commonly employed as transport vehicles to delivercargo to inflammatory areas for improved […]
Exosome Iv Infusion: A Promising Approach to Wellness and Recovery
Exosome therapy is a burgeoning field of regenerative medicine that utilizes the potential of exosomes, tiny extracellular vesicles, to facilitate healing and improve cellular function. Intravenous (IV) infusion of exosomes has emerged as a novel treatment, demonstrating promising results in clinical trials, such as reduced inflammation and improved metabolic processes. This article will explore the […]
Intravenous infusion of the exosomes derived from human umbilical cord mesenchymal stem cells enhance neurological recovery after traumatic brain injury via suppressing the NF-κB pathway
Abstract Traumatic brain injury (TBI) is a predominant cause of death and permanent disability globally. In recent years, much emphasis has been laid on treatments for TBI. Increasing evidence suggests that human umbilical cord mesenchymal stem cells (HUCMSCs) can improve neurological repair after TBI. However, the clinical use of HUCMSCs transplantation in TBI has been […]
Mesenchymal stem cells and mesenchymal stem cell-derived exosomes: a promising strategy for treating retinal degenerative diseases
Abstract Mesenchymal stem cells (MSCs) have emerged as a promising therapeutic strategy in regenerative medicine, demonstrating significant potential for clinical applications. Evidence suggests that MSCs not only exhibit multipotent differentiation potential but also exert critical therapeutic effects in retinal degenerative diseases via robust paracrine mechanisms. MSCs protect retinal cells from degenerative damage by modulating inflammation, […]
Therapeutic effect of mesenchymal stem cells and their derived exosomes in diseases
Abstract Mesenchymal stem cells (MSCs) are multipotent stem cells characterized by their robust proliferative capacity, homing ability, differentiation potential, and low immunogenicity in vitro. MSCs can be isolated from a variety of tissues, primarily including but not limited to bone marrow, adipose tissue, umbilical cord, placenta, and dental pulp. Although there have been a large […]
Progress of mesenchymal stem cells (MSCs) & MSC-Exosomes combined with drugs intervention in liver fibrosis
Abstract Liver fibrosis is an intrahepatic chronic damage repair response caused by various reasons such as alcoholic liver, fatty liver, viral hepatitis, autoimmune diseases, etc., and is closely related to the progression of liver disease. Currently, the mechanisms of liver fibrosis and its treatment are hot research topics in the field of liver disease remedy. […]
Application of Mesenchymal Stem Cells and Exosome alone or Combination Therapy as a Treatment Strategy for Wound Healing
Abstract The process of wound healing consists of multiple phases, and any disruptions in these phases can lead to the wound becoming chronic and impose heavy financial and psychological costs on the patient and a huge economic burden on the country’s healthcare system. Various treatments such as drugs, matrix and scaffolds, blood products, cell therapy, […]
Advances in mesenchymal stem cell and exosome-based therapies for aging and age-related diseases
Abstract Mesenchymal stem/stromal cells (MSCs) and their exosomes (MSC-Exos) have great potential for tissue repair and regenerative medicine, which can improve the symptoms and prognosis of aging-related diseases and potentially slow the aging process through multiple pathways. This comprehensive review summarizes the characterization of MSCs and MSC-Exos from various tissue sources and their applications in […]
Exosomes derived stem cells as a modern therapeutic approach for skin rejuvenation and hair regrowth
y genes involved in the key pathways of β-catenin, WNT, BMP2 and BMP4 promotes the proliferation of hair follicle stem cells Control hair loss Zhou et al. (2018), Zhang et al. (2022) Fat mesenchymal stem cell exosomes Inhibit the over-expression of MMP-1, MMP-2, MMP-3 and MMP-9 induced by UV irradiation, and enhance the expression of […]
Stem cell exosomes may be hypoxic pulmonary hypertension therapy
Researchers use lab-grown cells, rats to better understand disease mechanisms Margarida Maia, PhD avatar by Margarida Maia, PhD | July 28, 2025 A dropper is seen poised above one petri dish while an aerial view shows cells in another petri dish. Share on Facebook Share on Twitter Share on Reddit Share via Email Exosomes — […]