Two more people with HIV may be cured after stem cell transplants
Two more people appear to be free of HIV after stem cell transplants for cancer treatment, according to a pair of posters presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2025) this week in San Francisco. If the men remain in remission, they will be the ninth and tenth cases of a functional […]
Baby with spina bifida has promising future after fetal surgery with stem cells
By Erin Baily Dad reaching out to son who’s walking toward him Lindsey was 18 weeks pregnant with her fifth child when she got a life-changing phone call. Her blood work was abnormal. She and husband, Jared, went in for an ultrasound and got some news they never expected: Their developing baby had spina bifida. […]
Cord Blood Proven Effective for Cerebral Palsy
April 2025 What is new? A paper has just been published, in the prestigious peer-reviewed journal Pediatrics, which statistically demonstrates that cord blood cell therapy is an effective treatment for improving the gross motor skills of children with cerebral palsy (CP)1. This paper is the outcome of an international collaboration which performed an Individual […]
Diabetic Woman No Longer Needs Insulin After Single Dose of Experimental Stem Cells
A Canadian woman with type 1 diabetes spent nearly a decade dependent on her glucose monitor and insulin shots — but after a single dose of manufactured stem cells implanted into her liver, she’s now free. In an interview with CTV, 36-year-old Amanda Smith of London, Ontario described how it felt to be part of […]
‘My eye was saved by a placenta after acid attack’
Sharon Barbour Health correspondent, BBC North East and Cumbria BBC Paul Laskey is smiling. He is in a short sleeved top and sitting on his sofa at home. The white of his repaired eye is still quite red. BBC Paul Laskey’s eye has been saved with the help of a donated placenta A donated placenta […]
World-first stem-cell treatment restores vision in people
The treatment, given to four people with damaged corneas, seems safe but needs to be tested in larger trials. By Smriti Mallapaty Twitter Facebook Email Close up view of a human eye during a slit lamp eye examination. The transparent cornea is the outermost layer of the eye. Credit: Patrick Landmann/SPL Three people with severely […]
FDA Approves First Mesenchymal Stromal Cell Therapy to Treat Steroid-refractory Acute Graft-versus-host Disease
For Immediate Release: December 18, 2024 Today, the U.S. Food and Drug Administration approved Ryoncil (remestemcel-L-rknd), an allogeneic (donor) bone marrow-derived mesenchymal stromal cell (MSC) therapy indicated for the treatment of steroid-refractory acute graft-versus-host disease (SR-aGVHD) in pediatric patients 2 months of age and older. Ryoncil is the first FDA-approved MSC therapy. It contains MSCs, […]
Exosomal miR-133b-3p modulates TGF-β1/Treg immunomodulation to ameliorate osteoporosis
Abstract Purpose Osteoporosis (OP) is influenced by dysregulated miRNAs, particularly during osteoblast differentiation. The precise mechanisms are still under debate. This study aimed to explore the impact of bone marrow mesenchymal stem cells (BMSCs)-derived exosomal miR-133b-3p on the TGF-β1/Treg-mediated immune pathway, offering insights into OP’s pathogenesis and potential therapeutic targets. Materials and methods Bioinformatics analysis […]
Human umbilical cord mesenchymal stem cell-derived exosomes repair IBD by activating the SIRT1-FXR pathway in macrophages
Abstract Background Inflammatory bowel disease (IBD), a chronic immune disorder, has increasing global incidence and poor treatment outcome. Abnormal macrophage function is implicated in the pathophysiology of IBD. In this study, we investigated the mechanism by which human umbilical cord mesenchymal stem cell-derived exosomes (hucMSC-Ex) inhibit inflammation in IBD mouse and macrophage inflammation models. Methods […]
Stem cell therapy found to boost fertility in women with ovarian failure
Author(s)Celeste Krewson, Assistant Editor Fact checked by: Morgan Ebert, Managing Editor A new study reveals that stem cell treatment activates oocytes in 70% of women with ovarian failure. Stem cell therapy found to boost fertility in women with ovarian failure | Image Credit: © Anusorn – © Anusorn – stock.adobe.com. Stem cell therapy found to […]
